Monocytes, Manual Count, Body Fluid

What Are Monocytes?

Monocytes are a type of white blood cell produced in the bone marrow. They help the immune system fight infection and remove dead or damaged cells. They can move from the bloodstream into body tissues and fluids, especially during inflammation or infection.

Why Is a Manual Count Used?

A manual count involves a trained laboratory professional examining a stained slide of the fluid under a microscope. This method can provide a careful assessment of cell types, particularly when automated instruments give uncertain or incomplete results. It is often used for fluids such as cerebrospinal, pleural, peritoneal, or synovial fluid.

How the Sample Is Collected

The body fluid sample is typically collected by a clinician using a needle or other appropriate procedure, depending on the fluid type. The sample is then prepared on a slide, stained, and reviewed under a microscope.

What the Results Can Indicate

The presence and proportion of monocytes in a body fluid can help clinicians evaluate inflammation, infection, or other conditions. Monocytes may be increased in certain chronic or inflammatory processes, but results are interpreted together with other cell counts, fluid appearance, symptoms, and additional testing.