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Monocyte Substance Concentration in Cerebrospinal Fluid (CSF)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of monocytes, a type of white blood cell, in your cerebrospinal fluid (CSF). CSF is the fluid that surrounds your brain and spinal cord.

Quick summary

["Understanding your monocyte levels in CSF can help identify potential neurological or immune system issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
26486-1
Short code
Monocytes NFr CSF
Synonyms
Monocytes NFr CSF
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like headaches, neck stiffness, fever, or neurological problems that could suggest an infection, inflammation, or other condition affecting the brain or spinal cord. It may also be used to monitor certain conditions like meningitis or other immune-related disorders.

What to Expect During the Test

A small amount of CSF is collected through a procedure called a lumbar puncture (spinal tap). You’ll lie on your side and may feel a brief pinch as the needle is inserted into your lower back. The fluid is then sent to the lab for testing.

Preparation and Restrictions

No special preparation is usually needed. Avoid heavy lifting or strenuous activity for 24 hours before the procedure to reduce the risk of complications.

Possible Results and Interpretation

Results are interpreted by your healthcare provider based on your overall health, symptoms, and other test results. Elevated monocyte levels in CSF might indicate conditions such as infections, autoimmune diseases, or certain types of tumors.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Monocyte CSF Level

Frequently asked questions

What could high or low monocyte levels in CSF mean?
High levels of monocytes in CSF can suggest conditions like meningitis (infection), certain types of inflammation, or other immune responses affecting the central nervous system. Low levels may be less common but could be associated with certain neurological disorders or after treatment for infections.
How long will I need to wait for results?
Results from this test are typically available within a few days, depending on the lab’s processing time. Your doctor will discuss the results with you during a follow-up visit.
Can I drink alcohol before the lumbar puncture?
No, avoid alcohol for 24 hours before the procedure to reduce the risk of complications and ensure accurate test results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy