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Monocyte count in peripheral blood

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of monocytes, a type of white blood cell that helps fight infection and inflammation in your body.

Quick summary

["Monocytes help protect your body by responding to infections and tissue damage."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
71648-0
Short code
Monocytes NFr.DF Fld Manual
Synonyms
Monocytes NFr.DF Fld Manual
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might You Need This Test?

Your doctor may order this test to check for infections, inflammatory conditions, or other health issues that could affect your white blood cell counts. It can also help monitor certain treatments or conditions like leukemia or autoimmune diseases.

What Does a Result Mean?

Results are typically reported as the number of monocytes per microliter (µL) of blood. High or low counts may signal different health concerns, so your doctor will interpret the results in the context of your overall health and symptoms.

Sample Collection and Preparation

A small blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab for analysis. Monocytes are counted using a blood cell counter or automated analyzer.

Common Reasons for Testing

Tests for infections (such as tuberculosis or chronic infections), inflammatory diseases (like rheumatoid arthritis), or to evaluate the effectiveness of treatments targeting white blood cells.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Changes in monocyte levels can indicate underlying health issues, such as infections, immune system disorders, or certain cancers. High levels may suggest chronic inflammation or infections, while low levels might point to immune deficiencies or certain blood disorders.

Short name

Monocyte count

Frequently asked questions

What causes my monocyte count to be different from what’s expected?
Several factors can affect monocyte counts, including infections, chronic illnesses, medications, or certain medical conditions. If you have symptoms like fever, fatigue, or unexplained weight loss, discuss these with your doctor.
Is there anything I should do to prepare for this test?
No special preparation is usually needed. Avoid strenuous activity before the test, as it may temporarily affect your blood cell counts. Let your doctor know about any medications you’re taking.
Can high or low monocyte counts be dangerous?
Yes, significant deviations from normal levels can signal serious health concerns. High levels may require further investigation for infections or inflammation, while low levels could indicate immune system issues or other conditions. Your doctor will guide you on next steps based on your results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy