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Monocyte count (peripheral blood)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of monocytes, a type of white blood cell that helps your body fight infections and remove dead cells. Monocytes are part of your immune system and play a role in inflammation and healing.

Quick summary

["Monocyte count helps assess immune function and potential inflammation or infection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
95222-6
Short code
Monocytes NFr Stem prod Manual
Synonyms
Monocytes NFr Stem prod Manual
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test to evaluate your immune system, check for signs of infection, inflammation, or certain blood disorders. It can also help monitor conditions like chronic inflammation, autoimmune diseases, or after treatments like chemotherapy.

What to Expect Before the Test

No special preparation is needed for this test. A blood sample is taken from a vein, usually in your arm. You may feel a slight pinch, but it usually doesn’t cause discomfort. The process takes a few minutes.

What the Test Results Mean

Results are typically reported as the absolute count of monocytes per microliter (µL) of blood. While reference ranges can vary by lab, lower than expected counts may suggest immune suppression, while higher counts might indicate infection, inflammation, or certain blood disorders.

Common Conditions Monitored

This test is often used to monitor conditions like chronic inflammation (e.g., rheumatoid arthritis), infections, or to check for abnormalities in white blood cell counts before or after treatments that affect the immune system.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Monocyte levels can provide clues about your overall immune health. Low monocyte counts might signal conditions like severe infections, immune deficiencies, or certain cancers. High levels can be linked to infections, inflammatory diseases, or even some cancers. Always discuss your results with your healthcare provider for personalized interpretation.

Short name

Monocyte level

Frequently asked questions

How often will I need this test?
The frequency depends on your health condition and treatment plan. Your healthcare provider will determine how often you need this test based on your specific situation.
What are the normal ranges for this test?
Normal ranges can vary between labs and may depend on age and overall health. Typically, healthy adults have monocyte counts between approximately 0.1% and 1% of total white blood cells, or around 0.05 to 0.75 x 10³/µL. Your specific reference range will be provided by your lab report.
Can I eat or drink before this test?
No special diet or fasting is required for this test. You can eat and drink normally before having your blood drawn.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy