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Monocyte count (qualitative cell count of peripheral blood)

Published: August 9, 2026Updated: August 16, 2026

This test evaluates the number of monocytes, a type of white blood cell, in your blood. It may be used to assess immune function or identify potential infections, inflammation, or blood disorders.

Quick summary

["Monocytes help your body fight infections and respond to inflammation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72343-7
Short code
Monocytes/Rnd cells NFr Smn Manual
Synonyms
Monocytes/Rnd cells NFr Smn Manual
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
20
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
CPT
85651
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is a Monocyte Count Test Used For?

A qualitative monocyte count is often performed as part of a general blood test to help diagnose conditions like chronic infections, certain cancers (e.g., leukemia), or immune system disorders. It may also be used to monitor treatment responses in patients with ongoing health concerns.

How Is This Test Performed?

Blood is drawn from a vein, typically in your arm. The sample is then examined under a microscope to count the number of monocytes relative to other white blood cells. This is a manual process, meaning a trained lab technician directly observes and records the results.

What Does a Monocyte Count Tell You?

While this test provides a qualitative (non-numeric) assessment of monocyte presence, elevated or reduced levels may suggest underlying health issues. For example, high monocyte counts can indicate chronic inflammation or infection, while very low counts might point to immune deficiencies or certain blood disorders.

What Are Common Reasons for Testing?

Your healthcare provider may order this test if you have symptoms like persistent fevers, unexplained weight loss, fatigue, or if you’re undergoing treatment for conditions like cancer or autoimmune diseases. It may also be part of routine monitoring for patients with known immune or blood-related conditions.

Reference range

Adult males: 0-15 mm/hr; Females: 0-20 mm/hrN/A

Specimen: serum

No special preparation required. CRP may be affected by acute illness.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Monocytes play a key role in immune surveillance and tissue repair. Elevated monocyte counts can signal chronic inflammation, infections, or malignancies, while low counts may indicate immune suppression or certain blood disorders. This test is often used as part of a broader diagnostic evaluation rather than a standalone test for specific conditions.

Short name

Monocyte Screening Count

Frequently asked questions

Why might my doctor request this test?
Your doctor may recommend this test if you have symptoms like fatigue, unexplained weight changes, or if you’re being monitored for conditions that affect white blood cells, such as cancer, autoimmune diseases, or chronic infections.
What should I expect during the test?
You’ll have a small needle inserted into your arm to draw blood. The process takes a few minutes, and you may feel a brief pinch. The blood sample is then sent to the lab for manual cell counting under a microscope.
Can I eat or drink before this test?
No special preparation is needed for this test. However, always follow your doctor’s instructions regarding fasting or other restrictions if this is part of a larger blood workup.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy