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Monocyte count (qualitative manual cell differential)

Published: August 9, 2026Updated: August 16, 2026

This test checks the number of monocytes, a type of white blood cell, in your blood using a manual cell differential method. It helps identify if your monocyte levels are unusually high or low.

Quick summary

["Monocyte counts can signal infections, immune responses, or other health conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30145-7
Short code
Monocytes # Snv Manual
Synonyms
Monocytes # Snv Manual
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to evaluate symptoms like persistent fatigue, unexplained fever, or signs of chronic inflammation. It can also be part of a broader blood workup to monitor conditions like infections, autoimmune diseases, or certain cancers.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm or hand to draw blood. If you’re nervous, let your provider know—some people find it helpful to bring a distraction or ask for a tour of the lab beforehand.

What Happens During the Test?

Blood is drawn into a tube, then examined under a microscope by a trained technician. Unlike automated tests, this method involves counting each cell type manually, which can take longer.

What Are Normal Results?

Results are qualitative (descriptive rather than numeric), so they’ll indicate whether your monocyte count is within expected ranges or outside them. Your provider will interpret these results in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Monocyte Screening (Manual)

Frequently asked questions

What does a high monocyte count mean?
A high monocyte count may signal chronic inflammation, infections like tuberculosis, or autoimmune diseases. It could also be part of a broader immune response. Your provider will review your symptoms and other test results to determine the cause.
What causes low monocyte counts?
Low monocyte counts can result from bone marrow disorders, severe infections, immune deficiencies, or certain medications. If you notice symptoms like frequent infections or fatigue, talk to your provider about possible causes and next steps.
Is this test painful?
The blood draw itself may cause mild discomfort or bruising, but the manual cell differential process itself is not painful. Most people describe it as similar to a routine blood test. If you’re anxious, let your provider know—some options like numbing cream or a different vein may be available.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy