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Complete Blood Count (CBC) with Differential and Monocyte Subset Analysis

Published: August 9, 2026Updated: August 16, 2026

This test measures your blood’s overall health, including red blood cells, white blood cells, and a detailed breakdown of your monocytes—a type of white blood cell that helps fight infections.

Quick summary

["Understanding your white blood cell counts and subtypes helps doctors diagnose and manage conditions like infections, immune disorders, or blood diseases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
101146-9
Short code
Monocyte subsets panel Bld FC
Synonyms
Monocyte subsets panel Bld FC
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is a Complete Blood Count (CBC)?

A CBC is a standard blood test that provides key information about your blood’s composition, including red blood cells (for oxygen transport), white blood cells (for immunity), and platelets (for clotting). This test also includes a differential count, which breaks down the types of white blood cells, including monocytes, to help identify specific health concerns.

Why Might You Need This Test?

Your doctor may order this test to check for infections, inflammation, anemia, or blood disorders. Monocyte subset analysis can help pinpoint whether an infection or immune response is affecting your body, especially if symptoms like fatigue, fever, or unexplained swelling persist.

How Is This Test Performed?

A small blood sample is drawn from a vein, usually in your arm. The sample is then analyzed in a lab to measure the total number of white blood cells and their subtypes, including monocytes. Advanced techniques may further classify monocytes into subsets based on their size, shape, or functional markers.

What Do the Results Mean?

Results show your total white blood cell count, percentage of each type (including monocytes), and sometimes a breakdown of monocyte subsets. Elevated or low monocyte counts may signal infections, autoimmune diseases, or other conditions that require further medical evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CBC with Monocyte Breakdown

Frequently asked questions

How long does it take to get my results back?
Results are typically available within 24 to 48 hours, depending on your lab. Your doctor will discuss them with you during your follow-up visit.
Can I eat or drink before this test?
For standard CBC tests, you can eat and drink normally. If your doctor specifies fasting for other tests included in your panel, follow their instructions. Monocyte subset analysis does not require special preparation.
What are the most common reasons doctors order this test?
Common reasons include monitoring chronic conditions like leukemia or lymphoma, diagnosing infections (such as tuberculosis or chronic bacterial infections), evaluating immune system disorders, or assessing symptoms like persistent fatigue, fever, or unexplained weight loss.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy