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Monocyte Count in Serum (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence or absence of monocytes, a type of white blood cell, in your blood serum. It helps assess immune system function and identify potential infections, inflammation, or other blood disorders.

Quick summary

["Monocyte levels can signal immune health or hidden health risks."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
68424-1
Short code
Monocytes # Vitf Manual
Synonyms
Monocytes # Vitf Manual
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fever, fatigue, or unexplained infections. It could also be part of routine blood work to monitor chronic conditions like leukemia, autoimmune diseases, or immune deficiencies.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm for a blood draw. If you’re on blood thinners, let your provider know before the test.

What the Results Mean

A qualitative test doesn’t provide exact numbers, but it tells your doctor if monocytes are present or absent. High or low levels may indicate specific health concerns that need further investigation.

Common Reasons for Testing

This test is often used to diagnose or monitor conditions like chronic infections, certain cancers, or immune system disorders. It may also help track response to treatments for blood disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Monocytes play a key role in fighting infections and healing tissues. Abnormal levels can signal immune dysfunction, chronic inflammation, or underlying diseases requiring further evaluation by your healthcare team.

Short name

Monocyte Level Check

Frequently asked questions

What does a positive result mean?
A positive result (monocytes detected) suggests your immune system is active, possibly due to infection, inflammation, or other immune responses. Your doctor will discuss next steps based on your symptoms and medical history.
Can I get false results from diet or medications?
Diet or over-the-counter medications are unlikely to affect this qualitative test. However, certain medications (like steroids) may influence white blood cell counts. Always inform your provider about all medications.
How often should I get this test?
Your doctor will determine the frequency based on your health needs. Routine blood tests may include this test if you have chronic conditions or are at higher risk for immune-related issues.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy