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Monomethylphosphonic acid (MMPA) in urine

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of monomethylphosphonic acid, a chemical often associated with exposure to certain industrial or environmental toxins, including organophosphates.

Quick summary

["This test helps assess potential exposure to harmful substances that may affect your health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
54102-9
Short code
Monoethyl Me-phosphonate Ur-mCnc
Synonyms
Monoethyl Me-phosphonate Ur-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Is This Test Measuring?

Monomethylphosphonic acid (MMPA) is a breakdown product of organophosphates, a class of chemicals used in pesticides, herbicides, and industrial processes. High levels in urine may indicate recent exposure to these substances, though it is not a definitive test for poisoning alone.

Why Might You Need This Test?

Your healthcare provider may order this test if you’ve been exposed to suspected organophosphate-containing substances (e.g., agricultural chemicals, industrial accidents) or if symptoms like muscle weakness, confusion, or respiratory issues are present.

What Does the Result Mean?

Results are not typically provided as a single reference range since MMPA levels vary widely based on exposure timing, duration, and metabolism. Elevated levels suggest recent exposure, but they do not confirm poisoning without clinical correlation.

What Are Common Symptoms?

Organophosphate exposure may cause symptoms like nausea, dizziness, or neurological effects, but MMPA alone does not diagnose poisoning. Symptoms can range from mild to severe and may require immediate medical attention.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Role in Diagnosis and Monitoring

Short name

MMPA Urine

Frequently asked questions

Why is this test important in a clinical setting?
This test helps identify potential exposure to harmful chemicals but is not a standalone diagnostic tool for poisoning. It is often used alongside clinical evaluation and other tests to assess risk or guide further investigation.
How does this test differ from other organophosphate tests?
Unlike direct organophosphate measurements, MMPA is a metabolite detected in urine, offering a broader window of exposure detection. It is less specific but useful for screening in occupational or environmental settings.
What should I do if I suspect exposure?
Seek immediate medical attention if you experience symptoms like confusion, muscle weakness, or difficulty breathing. Report any known exposure to chemicals to your healthcare provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy