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Monocyte Count (Peripheral Blood)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of monocytes, a type of white blood cell, in your blood. Monocytes help fight infections and inflammation.

Quick summary

["Your doctor may check monocyte levels to diagnose or monitor conditions affecting white blood cells or immune function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
96268-8
Short code
Mono.PD-L1/Monocytes NFr Bld FC
Synonyms
Mono.PD-L1/Monocytes NFr Bld FC
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors order monocyte tests to evaluate immune system health, detect infections, or investigate symptoms like fatigue, fever, or unexplained weight loss. It may also be used before surgery or during chemotherapy to monitor immune response.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm or hand to draw blood. If you’re on blood thinners, let your doctor know before the test.

What the Test Results Mean

Results are reported as the absolute count of monocytes per microliter of blood. High or low levels can signal underlying health issues, such as infections, autoimmune disorders, or certain cancers.

Common Conditions Monitored

Monocyte counts are often checked in patients with chronic diseases like rheumatoid arthritis, lupus, or HIV, or after treatments like chemotherapy that weaken the immune system.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated monocytes may indicate chronic inflammation, infections, or certain cancers. Low monocyte counts can suggest immune deficiencies, bone marrow disorders, or severe infections. Always discuss results with your healthcare provider for personalized guidance.

Short name

Monocyte Level

Frequently asked questions

How long does it take to get my results?
Test results are typically available within 1 to 3 business days, depending on your lab’s processing time.
What does a normal monocyte count mean?
A normal monocyte count is not a fixed number, as it can vary slightly by lab. Your doctor will compare your results to your baseline or clinical context to determine if they’re within expected ranges.
Can I eat or drink before this test?
You can eat and drink normally before this test, as it doesn’t require fasting.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy