Cerebrospinal Fluid (CSF) Monocyte and Macrophage Cell Count
This test measures the number of immune cells (monocytes and macrophages) in your cerebrospinal fluid (CSF), which is the fluid surrounding your brain and spinal cord. These cells help protect against infections and inflammation in the central nervous system.
["Understanding your CSF immune cell count can help diagnose or monitor conditions affecting your brain and spinal cord."]
Key facts at a glance
- LOINC
- 35025-6
- Short code
- Monos+Macros # CSF
- Synonyms
- Monos+Macros # CSF
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like headaches, neck stiffness, fever, confusion, or neurological issues that suggest an infection, inflammation, or other condition affecting the brain or spinal cord. It’s often used alongside other tests to guide diagnosis.
What to Expect Before the Test
You’ll likely have a lumbar puncture (spinal tap) performed by a healthcare professional. This involves inserting a needle into your lower back to collect a small sample of CSF. The procedure is usually quick and may cause mild discomfort, but you’ll be given instructions to rest afterward.
What the Test Results Mean
The results focus on identifying abnormal numbers of monocytes and macrophages, which can indicate conditions like meningitis, encephalitis, multiple sclerosis, or other inflammatory or infectious processes in the central nervous system. Your results will be interpreted by a healthcare provider based on your symptoms and other test findings.
Common Conditions Monitored or Diagnosed
This test helps diagnose or monitor conditions such as viral or bacterial meningitis, encephalitis, subarachnoid hemorrhage, Guillain-Barré syndrome, or certain types of brain tumors. Elevated counts may also suggest chronic inflammatory diseases.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
CSF Mononuclear Cells (Qualitative Count)
Frequently asked questions
What does a high or low CSF monocyte/macrophage count indicate?
How long does it take to get results from this test?
Is this test painful?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy