Skip to content

Monocyte and Macrophage Fluid Protein Profile (Manual Qualitative Analysis)

Published: August 9, 2026Updated: August 16, 2026

This test evaluates protein composition in a body fluid sample to assess the presence of monocytes and macrophages, which are immune cells involved in inflammation and immune response. It may be used to diagnose or monitor conditions affecting these cells.

Quick summary

["This test helps identify protein patterns linked to immune cell activity in fluid samples, often used in research or specialized diagnostic contexts."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
76408-4
Short code
Monos+Macros Fld Manual
Synonyms
Monos+Macros Fld Manual
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is This Test Measuring?

The test analyzes proteins in a fluid sample (likely blood, lymph, or other bodily fluid) to detect specific markers associated with monocytes and macrophages. These cells play a key role in immune defense, and their proteins can reflect underlying health conditions, such as infections, autoimmune diseases, or chronic inflammation.

Why Might You Need This Test?

This test may be ordered for specialized diagnostic purposes, such as evaluating immune system function, identifying rare blood disorders, or assessing fluid-based samples in research or clinical trials. It is not commonly used for routine care.

How Is the Sample Collected?

A small amount of fluid (e.g., blood, lymph, or other bodily fluid) will be drawn from a vein or collected via other methods, depending on the clinical need. The sample is then processed manually for protein analysis.

What Does the Result Mean?

Results are qualitative (descriptive rather than numerical) and may indicate abnormal protein patterns linked to immune cell activity. Your healthcare provider will interpret the findings in the context of your medical history and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

None

Frequently asked questions

What is the purpose of this manual qualitative analysis?
This test is used to detect specific protein patterns in fluid samples that can indicate the presence or activity of monocytes and macrophages. It helps healthcare providers diagnose or monitor conditions affecting these immune cells, often in research or specialized clinical contexts.
No special preparation is typically required, but follow any instructions your healthcare provider gives you regarding fasting, hydration, or avoiding certain medications. The sample collection may be timed based on clinical needs.
Results may take longer than standard lab tests due to manual processing. Your provider will discuss timelines with you based on the specific clinical context. Follow-up may be needed to interpret findings.
Is this test covered by insurance?
Coverage depends on medical necessity and your insurance plan. Check with your provider or insurance company to confirm if this specialized test is approved for your situation.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy