Monocyte and Macrophage Protein Levels in Cerebrospinal Fluid (CSF)
This test measures proteins associated with immune cells (monocytes and macrophages) found in your spinal fluid. It helps assess inflammation or immune activity in the central nervous system.
["Evaluates immune cell activity in spinal fluid for potential neurological conditions."]
Key facts at a glance
- LOINC
- 30436-0
- Short code
- Monos+Macros NFr CSF
- Synonyms
- Monos+Macros NFr CSF
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your doctor may recommend this test if you have symptoms like headaches, neck stiffness, confusion, or neurological issues that suggest inflammation or infection in the brain or spinal cord. It could also be part of a broader evaluation for autoimmune diseases or conditions affecting the central nervous system.
What to Expect Before the Test
No special preparation is needed. You’ll have a small needle inserted into your lower back to collect a small amount of spinal fluid. You may feel a brief pinch, but it’s usually over quickly. You’ll lie on your side for a few minutes afterward to prevent any leakage.
What the Results Mean
Higher-than-normal levels of these proteins may indicate inflammation, infection, or immune activity in your spinal fluid. Lower-than-normal levels might suggest reduced immune response or certain neurological disorders. Your doctor will interpret results in the context of your symptoms and medical history.
Common Conditions This Test Helps Diagnose
This test can help diagnose or monitor conditions such as multiple sclerosis, meningitis, encephalitis, or other inflammatory or infectious processes in the central nervous system.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
CSF Monocyte/Macrophage Profile
Frequently asked questions
What does a high or low result mean for my health?
Does this test require fasting?
How long will it take to get my results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy