Skip to content

Monocyte and Macrophage Protein Levels in Cerebrospinal Fluid (CSF)

Published: August 9, 2026Updated: August 16, 2026

This test measures proteins associated with immune cells (monocytes and macrophages) found in your spinal fluid. It helps assess inflammation or immune activity in the central nervous system.

Quick summary

["Evaluates immune cell activity in spinal fluid for potential neurological conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30436-0
Short code
Monos+Macros NFr CSF
Synonyms
Monos+Macros NFr CSF
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like headaches, neck stiffness, confusion, or neurological issues that suggest inflammation or infection in the brain or spinal cord. It could also be part of a broader evaluation for autoimmune diseases or conditions affecting the central nervous system.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your lower back to collect a small amount of spinal fluid. You may feel a brief pinch, but it’s usually over quickly. You’ll lie on your side for a few minutes afterward to prevent any leakage.

What the Results Mean

Higher-than-normal levels of these proteins may indicate inflammation, infection, or immune activity in your spinal fluid. Lower-than-normal levels might suggest reduced immune response or certain neurological disorders. Your doctor will interpret results in the context of your symptoms and medical history.

Common Conditions This Test Helps Diagnose

This test can help diagnose or monitor conditions such as multiple sclerosis, meningitis, encephalitis, or other inflammatory or infectious processes in the central nervous system.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CSF Monocyte/Macrophage Profile

Frequently asked questions

What does a high or low result mean for my health?
A high result may suggest inflammation, infection, or an immune response in your spinal fluid, which could indicate conditions like meningitis, encephalitis, or certain autoimmune diseases. A low result might suggest reduced immune activity or could be part of a broader evaluation for neurological disorders.
Does this test require fasting?
No fasting is required for this test. It involves collecting spinal fluid, so preparation focuses on staying hydrated and avoiding straining before the procedure.
How long will it take to get my results?
Results are typically available within a few days to a couple of weeks, depending on your lab’s processing time. Your doctor will contact you once they have the results and discuss them with you.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy