Macro/microscopic examination of fluid (manual cell count and differential)
This test involves a visual and manual count of cells in a fluid sample, such as blood, urine, or cerebrospinal fluid, to identify and assess the types and numbers of cells present.
["Helps diagnose infections, inflammation, or other conditions by examining cell types in bodily fluids."]
Key facts at a glance
- LOINC
- 21394-2
- Short code
- Monos+Macros NFr Fld Manual
- Synonyms
- Monos+Macros NFr Fld Manual
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- manual-count
- CPT
- 86430
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is This Test Used For?
This test is primarily used to detect abnormal cell counts or types in fluids like blood, urine, or spinal fluid. It helps identify conditions such as infections (e.g., bacterial or viral), blood disorders (e.g., leukemia), kidney issues, or neurological problems (e.g., meningitis).
How Is the Sample Collected?
A small amount of fluid is collected via a needle or catheter, depending on the type of fluid being tested. For example, blood is drawn from a vein, while urine or spinal fluid may be collected through a catheter or needle inserted into the body. The sample is then sent to the lab for microscopic and manual cell counting.
What Does the Test Involve?
The lab technician examines the fluid under a microscope to count and identify different cell types, such as red blood cells, white blood cells, and sometimes specialized cells like macrophages or neutrophils. Manual cell differentiation ensures accuracy for conditions requiring detailed cell analysis.
How Are Results Interpreted?
Results are reported as counts of specific cell types (e.g., total white blood cell count, percentage of neutrophils or lymphocytes). Abnormal counts or cell types may signal underlying health issues that require further medical evaluation.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
None
Frequently asked questions
Why might my doctor order this test?
How long does it take to get results?
What are common reasons for abnormal results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy