Serum/plasma protein electrophoresis with bromocresol green staining

What This Test Measures

Electrophoresis separates proteins in your blood based on size and electrical charge. Bromocresol green dye binds to specific protein groups, allowing for visual differentiation of albumin, alpha, beta, and gamma globulins. This helps detect imbalances that may indicate conditions like infections, autoimmune diseases, or cancer.

Common Uses

This test is primarily used to diagnose and monitor conditions affecting protein levels, such as multiple myeloma (cancer of plasma cells), liver disease, kidney disease, or certain immune disorders. It can also help assess protein malnutrition or track responses to treatments.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate serum or plasma, which is sent to the lab for electrophoresis. No special preparation is needed, but fasting may be advised depending on your specific test protocol.

What to Expect Before the Test

You may experience mild discomfort or bruising at the injection site. Avoid eating or drinking for 8–12 hours before the test if fasting is required. Wear comfortable clothing and let your healthcare provider know about any medications or allergies.