Monocyte and Macrophage Cell Count with Differential Analysis (Serum/Plasma Leukocyte Profile)
This test measures the number and types of white blood cells, specifically focusing on monocytes and macrophages, often analyzed alongside other blood cell types for immune assessment.
["Understanding your immune cell composition can help identify infections, inflammation, or immune disorders."]
Key facts at a glance
- LOINC
- 32194-3
- Short code
- Monos+Macros Plr Ql Micro
- Synonyms
- Monos+Macros Plr Ql Micro
- Category
- chemistry
- Sample
- fluid
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- microscopy-light
- Specimen volume
- 2-5 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h
- Hemolysis max
- 300
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test evaluates the concentration of monocytes and macrophages, which are types of white blood cells involved in immune responses. It may also include a differential count of other blood cells (e.g., neutrophils, lymphocytes) to assess overall immune function and potential abnormalities.
Why It’s Done
Doctors may order this test to diagnose or monitor conditions like infections, autoimmune diseases, leukemia, or chronic inflammatory disorders. It helps determine how well your immune system is functioning or if certain cell types are elevated or suppressed.
Sample Collection and Preparation
A blood sample is drawn from a vein, typically in your arm. The sample is processed to separate cells from plasma/serum, then analyzed to count and identify different white blood cell types, including monocytes and macrophages.
Common Conditions Monitored
Results may be used to assess immune system health, detect infections (e.g., bacterial or fungal), evaluate chronic conditions like rheumatoid arthritis or lupus, or monitor treatment responses in cancer or autoimmune diseases.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal monocyte or macrophage counts can signal underlying health issues. For example, high levels may indicate chronic inflammation or infections, while low levels could suggest immune deficiencies or certain cancers. Always discuss results with your healthcare provider for personalized interpretation.
Short name
None
Frequently asked questions
What does a high or low monocyte/macrophage count mean?
How often should I get this test?
Can diet or lifestyle affect these test results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy