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Serum or plasma concentration of a substance related to protein electrophoresis (qualitative or semi-quantitative screening)

Published: August 9, 2026Updated: August 16, 2026

This test measures the different types of proteins in your blood, helping identify abnormalities that may signal conditions like kidney disease, liver problems, or certain cancers.

Quick summary

["Protein electrophoresis helps detect unusual protein patterns that could indicate health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
85715-1
Short code
Mo preg rubella symp Mother
Synonyms
Mo preg rubella symp Mother
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Protein Electrophoresis Used For?

Protein electrophoresis separates blood proteins into distinct bands based on size and charge. This process can reveal imbalances, such as high levels of abnormal proteins (e.g., monoclonal gammopathy) or low levels of essential proteins (e.g., albumin). It’s often used as a screening tool for conditions like multiple myeloma, amyloidosis, or chronic kidney disease.

How Is This Test Performed?

A small blood sample is drawn from your arm. The serum or plasma is then placed in a gel and subjected to an electric current. Proteins migrate toward the opposite charge, creating visible bands that are analyzed for composition and quantity.

What Does the Test Result Mean?

Results may show distinct bands, smears, or unusual patterns. For example, a prominent band in a specific region might indicate an abnormal protein. Your healthcare provider will interpret the results in the context of your symptoms and medical history.

Common Conditions Linked to Protein Electrophoresis

This test can help diagnose or monitor conditions like multiple myeloma (a cancer of plasma cells), kidney disease, liver disease, or certain autoimmune disorders. It may also be used to screen for hidden protein abnormalities in chronic illnesses.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Protein electrophoresis is critical for identifying protein abnormalities that standard blood tests might miss. It provides a snapshot of protein distribution, guiding further testing or treatment decisions when other markers are unclear.

Short name

Protein Electrophoresis (Screening)

Frequently asked questions

Why might my doctor order this test?
Your doctor may recommend protein electrophoresis if you have symptoms like unexplained weight loss, fatigue, swelling, or if they suspect conditions like multiple myeloma, kidney disease, or liver dysfunction. It’s also sometimes used as part of routine monitoring for chronic illnesses.
What should I expect during or after the test?
The blood draw is quick and typically painless. You may feel slight discomfort, but there’s no downtime. Results are usually ready within a few days, depending on lab processing.
Do I need to prepare for this test?
No special preparation is needed. Avoiding certain medications (like blood thinners) may be advised if your doctor specifies it, but this is rare for routine protein electrophoresis.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy