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Morphine and Creatinine, Urine — Body-Mass-Adjusted Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures morphine and creatinine in urine. Creatinine can help account for urine concentration when interpreting the morphine result.

Quick summary

["This test can help determine whether morphine is present in the urine and how the result should be interpreted."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
78768-9
Short code
Morphine adj bodymass+crea Ur-mCnc
Synonyms
Morphine adj bodymass+crea Ur-mCnc
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount, or mass concentration, of morphine in urine. It may also include a urine creatinine measurement, which helps show how concentrated the urine sample is.

Why might I need this test?

Urine morphine testing may be used in workplace or school drug testing, monitoring of prescribed pain medicines, or investigation of possible opioid exposure. A clinician may order it when symptoms suggest recent opioid use.

How is the test performed?

A urine sample is collected and analyzed in a laboratory, often using a method designed to identify and measure substances such as morphine. The laboratory report identifies the method and the units used for each result.

How do I prepare for the test?

Follow the collection instructions provided by the laboratory or clinician. Do not deliberately drink large amounts of water, and tell the healthcare professional about medicines or substances that could affect the result.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine Morphine and Creatinine

Frequently asked questions

Does a detectable morphine result mean someone used morphine?
Not necessarily. It may reflect morphine medication, exposure to another opioid that can be detected as morphine, or contamination in some circumstances. The healthcare professional will review the result with the rest of the person's history.
Why is urine creatinine included?
Creatinine helps indicate how concentrated or dilute the urine is. This matters because the same amount of a substance can produce different urine concentrations depending on fluid intake and other factors.
Can morphine disappear quickly from the urine?
Yes. The amount detectable in urine can change relatively quickly, so a result reflects exposure within a particular time window rather than proving exactly when exposure occurred. The collection time and circumstances are important for interpretation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy