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Serum morphine mass concentration (quantitative drug screening)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of morphine present in your blood serum, often used to assess recent opioid exposure or monitor drug levels in medical settings.

Quick summary

["This test helps track opioid use or confirm recent ingestion of morphine-containing medications."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73972-2
Short code
Morphine Free Bld-mCnc
Synonyms
Morphine Free Bld-mCnc
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

Morphine is a powerful opioid pain reliever. This test detects its presence in your blood, measured in micrograms per milliliter (mcg/mL). It may be used to screen for opioid use, evaluate overdose risk, or assess therapeutic drug levels in certain clinical scenarios.

Why It Might Be Ordered

Your healthcare provider may request this test if you’ve been prescribed morphine, if you’re suspected of opioid misuse, or if you’re experiencing symptoms like confusion, slowed breathing, or unusual sleepiness that could indicate opioid exposure.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The blood is processed to separate serum (the liquid part without clotting factors), which is then tested for morphine levels. This process is quick and usually done in a lab setting.

What to Expect Before the Test

No special preparation is needed, but inform your doctor about any medications you’re taking, including over-the-counter drugs or supplements, as they could affect results. Avoid alcohol before the test if instructed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High morphine levels may indicate recent opioid use, potential overdose, or improper medication administration. Low or undetectable levels may suggest recent abstinence or rapid metabolism. Results guide treatment decisions, such as adjusting dosages or identifying misuse patterns.

Short name

Serum morphine level

Frequently asked questions

How long does it take to get results?
Results are typically available within 1–2 business days, depending on lab processing times. Your healthcare provider will discuss them with you during your follow-up visit.
Can I drink water before this test?
Yes, you can drink water as needed unless your doctor specifies otherwise. Avoid excessive fluids that might dilute your blood sample, as this could affect morphine measurement.
Will this test show other opioids besides morphine?
This test specifically measures morphine. If other opioids (like heroin metabolites or different prescription opioids) are suspected, additional tests may be needed.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy