Serum Morphine Mass Concentration (24-Hour Urine Collection)
This test measures the amount of morphine present in your urine over a 24-hour period. It helps assess recent opioid use, including prescription pain relievers or illicit opioids like heroin.
["This test helps doctors track opioid exposure and monitor for misuse or adherence to treatment plans."]
Key facts at a glance
- LOINC
- 19604-8
- Short code
- Morphine Free CtO Ur Cfm-mCnc
- Synonyms
- Morphine Free CtO Ur Cfm-mCnc
- Category
- chemistry
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- confirm
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Your healthcare provider may order this test if you’re taking opioids for pain management, recovering from opioid use, or if there’s suspicion of opioid misuse. It can also be used to verify compliance with treatment programs or screen for substance use in certain settings like workplaces or legal cases.
What Does the Test Involve?
You’ll collect all your urine over a full 24-hour period and submit it in one container. The lab will analyze the combined sample for morphine levels. This method provides a broader picture of opioid exposure than a single urine sample.
What to Expect Before the Test
No special preparation is needed, but avoid drinking excessive amounts of fluids that day to ensure a complete collection. If you’re on certain medications (like diuretics), discuss this with your provider before collecting urine.
What to Expect After the Test
Results are typically reported as a mass concentration of morphine in the urine sample. You’ll receive a written report from your healthcare provider, who will interpret the results in the context of your medical history and treatment goals.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
High morphine levels may indicate recent opioid use, including misuse or non-compliance with prescribed doses. Low or absent levels could suggest abstinence or reduced exposure. This test is particularly useful in monitoring patients in opioid treatment programs, assessing pain management effectiveness, or evaluating for illicit opioid use.
Short name
Morphine Urine Drug Screen (24-hour)
Frequently asked questions
How long does it take to get results?
What does a positive result mean?
Can I drink alcohol before giving my urine sample?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy