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Urine Morphine Free (24-Hour Collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of morphine (a metabolite of codeine and morphine) not present in your urine over a 24-hour period. It helps assess drug exposure, particularly in cases of suspected opioid use or monitoring therapeutic drug levels.

Quick summary

["This test helps doctors track opioid-related exposure or confirm abstinence from opioids."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110571-7
Short code
Morphine Free Msmt Ur
Synonyms
Morphine Free Msmt Ur
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’re being monitored for opioid use, suspected drug abuse, or managing chronic pain with opioids. It can also be used in legal or workplace drug screening contexts.

What to Expect Before the Test

You’ll collect all urine produced in a 24-hour period in a special container. The test doesn’t require fasting or special preparation beyond following standard urine collection instructions.

How the Test Works

The collected urine is analyzed to detect morphine metabolites, which are not naturally present in healthy individuals. The test uses a sensitive method to measure these substances accurately.

What the Results Mean

A positive result indicates recent opioid exposure, while a negative result suggests no detectable morphine metabolites in your urine. Results are interpreted by your healthcare provider in the context of your medical history and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test is critical for confirming opioid use, monitoring treatment adherence, or detecting potential misuse. It helps differentiate between therapeutic opioid use and illicit drug exposure, guiding appropriate medical or legal decisions.

Short name

Urine Free Morphine

Frequently asked questions

What does a positive result mean?
A positive result means morphine metabolites were found in your urine, indicating recent opioid exposure. This could be due to prescribed opioids, illegal use, or both. Your provider will discuss next steps based on your situation.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times. Follow-up with your healthcare provider to discuss the findings.
Can I drink alcohol before this test?
Alcohol itself does not affect this test, but it’s important to follow all instructions provided by your lab or healthcare provider regarding urine collection and timing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy