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Methylated Penetrans DNA (Plasma/Serum) by Quantitative Nucleotide Amplification Probe

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of methylated DNA fragments in your blood, which may help assess certain genetic or epigenetic changes.

Quick summary

["A blood test to detect abnormal DNA methylation patterns that could relate to genetic risks or conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47965-9
Short code
M penetrans DNA Spec Ql NAA+probe
Synonyms
M penetrans DNA Spec Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects methylated DNA fragments, which are small pieces of genetic material that have undergone chemical changes (methylation). These changes can be linked to how genes are expressed and may appear in conditions like certain cancers or genetic disorders.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have a family history of genetic conditions, cancer risk factors, or if you’re being evaluated for conditions involving epigenetic changes.

Sample Collection and Preparation

A blood sample is drawn, and the plasma or serum is processed to extract DNA fragments. The test uses a specialized probe to detect methylated sequences during amplification.

What to Expect Before the Test

No special preparation is needed, but fasting may not be required unless instructed by your doctor. Wear comfortable clothing for blood draw.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Methylated DNA Test

Frequently asked questions

What does a positive result mean?
A positive result suggests the presence of methylated DNA fragments, which may signal a higher risk for genetic or epigenetic conditions. Your doctor will interpret results in the context of your medical history and symptoms.
How soon will I get results?
Results are typically available within 1–2 weeks, depending on lab processing times. Your healthcare provider will discuss them with you.
Can this test be used for screening?
This test is not a general screening tool but may be used in specific clinical scenarios, such as cancer risk assessment or research studies. Always ask your doctor about its purpose for your situation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy