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Pneumococcal polysaccharide antibody screening (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies to *Pneumococcus* bacteria, a common cause of pneumonia, meningitis, and other infections. It helps assess immunity after vaccination or exposure.

Quick summary

["Checks if your body has developed protection against pneumococcal infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17303-9
Short code
M pneumo Ab CSF-aCnc
Synonyms
M pneumo Ab CSF-aCnc
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Matters

Pneumococcal bacteria can lead to serious illnesses, especially in people with weakened immune systems, older adults, or those with chronic health conditions. This test helps determine if your immune response is adequate after vaccination or natural exposure.

What to Expect Before the Test

No special preparation is needed. A blood sample will be drawn from a vein in your arm. You may feel slight discomfort, but it usually lasts only a few minutes. If you’re on blood-thinning medication, let your provider know before the test.

What the Results Mean

Results are qualitative (yes/no) and indicate whether detectable antibodies are present. High levels suggest immunity, while low or absent levels may mean you need booster vaccination or further evaluation.

Common Reasons for This Test

Your doctor may order this test if you’ve received the pneumococcal vaccine but have concerns about immunity, if you’ve had recent pneumococcal infections, or if you’re at high risk for complications from these bacteria.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test is primarily used to confirm immunity post-vaccination or to identify individuals who may benefit from additional vaccination. It’s not a diagnostic tool for active infections but helps guide preventive measures.

Short name

Pneumococcal Antibody Screen

Frequently asked questions

Will I need to fast before this test?
No fasting is required. Blood tests like this are typically done when you’re comfortably seated and well-hydrated.
What does a positive result mean?
A positive result means your body has produced antibodies against pneumococcal bacteria, indicating a likely immune response. This could be from vaccination or prior exposure.
Can I still get pneumococcal infections even if my test is positive?
Yes, while a positive test suggests immunity, pneumococcal bacteria can still cause infections. Vaccination remains the best protection, and other preventive measures (like handwashing) are still recommended.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy