Pneumococcal Antibody (IgM) in Serum
This test measures the presence of IgM antibodies in your blood that your immune system produces in response to infection by *Streptococcus pneumoniae* (pneumococcus). IgM antibodies are typically detected shortly after infection begins.
["IgM antibodies help identify recent pneumococcal infections but may not persist long-term."]
Key facts at a glance
- LOINC
- 111443-8
- Short code
- M pneumo Ab Msmt Ser
- Synonyms
- M pneumo Ab Msmt Ser
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
IgM antibodies are a type of antibody your immune system makes early in an infection. This test detects these antibodies in your serum to help determine if you’ve recently been exposed to *Streptococcus pneumoniae*, which can cause pneumonia, meningitis, or other serious illnesses.
When This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms of pneumonia, flu-like illness, or other infections that could be caused by pneumococcus, especially if you’re at higher risk (e.g., elderly, immunocompromised, or with underlying health conditions). It may also be used to investigate unexplained infections or as part of diagnostic workup.
How the Test Works
A small blood sample is drawn from your arm. The serum portion of the blood is then tested using an immunoassay method to detect IgM antibodies specific to pneumococcal bacteria. This helps identify if your immune system has recently responded to infection.
What the Results Mean
A positive result indicates recent exposure or infection with *Streptococcus pneumoniae*, as your body has produced IgM antibodies. A negative result suggests either no recent exposure or that the infection has cleared or that IgM levels are too low to detect. Results alone do not confirm a diagnosis; they are used alongside clinical symptoms and other tests.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
IgM Antibody to *Streptococcus pneumoniae* (Serum)
Frequently asked questions
Why might my doctor order this test?
What does a positive result mean for my health?
Can I get this test at home?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy