Skip to content

Pneumococcal Antibody (IgM) in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of IgM antibodies in your blood that your immune system produces in response to infection by *Streptococcus pneumoniae* (pneumococcus). IgM antibodies are typically detected shortly after infection begins.

Quick summary

["IgM antibodies help identify recent pneumococcal infections but may not persist long-term."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
111443-8
Short code
M pneumo Ab Msmt Ser
Synonyms
M pneumo Ab Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

IgM antibodies are a type of antibody your immune system makes early in an infection. This test detects these antibodies in your serum to help determine if you’ve recently been exposed to *Streptococcus pneumoniae*, which can cause pneumonia, meningitis, or other serious illnesses.

When This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms of pneumonia, flu-like illness, or other infections that could be caused by pneumococcus, especially if you’re at higher risk (e.g., elderly, immunocompromised, or with underlying health conditions). It may also be used to investigate unexplained infections or as part of diagnostic workup.

How the Test Works

A small blood sample is drawn from your arm. The serum portion of the blood is then tested using an immunoassay method to detect IgM antibodies specific to pneumococcal bacteria. This helps identify if your immune system has recently responded to infection.

What the Results Mean

A positive result indicates recent exposure or infection with *Streptococcus pneumoniae*, as your body has produced IgM antibodies. A negative result suggests either no recent exposure or that the infection has cleared or that IgM levels are too low to detect. Results alone do not confirm a diagnosis; they are used alongside clinical symptoms and other tests.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgM Antibody to *Streptococcus pneumoniae* (Serum)

Frequently asked questions

Why might my doctor order this test?
Your doctor may order this test to help diagnose or monitor infections caused by *Streptococcus pneumoniae*, particularly if symptoms like fever, cough, or confusion are present. It can also be useful in evaluating patients with unexplained infections or those at higher risk of complications from pneumococcal disease.
What does a positive result mean for my health?
A positive result suggests recent exposure to pneumococcus, which may indicate an active infection. This can guide treatment decisions, such as starting antibiotics if needed. However, results should always be interpreted by your healthcare provider in the context of your symptoms and medical history.
Can I get this test at home?
No, this test requires a blood sample collected by a healthcare professional in a clinical setting. Results are typically reviewed and discussed with your doctor.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy