: Mycoplasma pneumoniae Antibody, Cerebrospinal Fluid
: This test looks for antibodies against the bacterium Mycoplasma pneumoniae in a sample of cerebrospinal fluid (the fluid that surrounds the brain and spinal cord), which can help evaluate whether this organism may be involved in a neurologic or meningeal process.
[": The test detects antibodies to Mycoplasma pneumoniae in spinal fluid and is interpreted together with symptoms, other lab tests, and imaging."]
Key facts at a glance
- LOINC
- 42993-6
- Short code
- M pneumo Ab Titr CSF
- Synonyms
- M pneumo Ab Titr CSF
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
: What This Test Measures
: The assay detects antibodies (immune proteins) that the body produces in response to Mycoplasma pneumoniae, a common respiratory bacterium that can occasionally cause infection outside the lungs, including the nervous system. Finding these antibodies in cerebrospinal fluid may support suspicion of an associated neurologic involvement.
: Why Cerebrospinal Fluid Is Tested
: Cerebrospinal fluid is collected by lumbar puncture (spinal tap). Testing this fluid rather than blood helps your care team look for signs of inflammation or infection directly within the central nervous system, alongside cell counts, protein, glucose, and other studies.
: How Results Are Interpreted
: Results for CSF antibody testing are not read in isolation. Antibody testing can be affected by antibody that has crossed from blood into spinal fluid, so clinicians compare CSF and blood findings and consider the overall picture. A positive or negative result alone does not confirm or exclude infection.
: What to Expect
: A lumbar puncture is usually performed after other considerations and with local numbing. Most people tolerate it well and recover quickly; your care team will explain preparation, risks, and aftercare. Laboratory turnaround varies by facility.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
: M. pneumoniae Ab, CSF
Frequently asked questions
: Does a positive result mean I definitely have a Mycoplasma infection in my nervous system?
: Will I need a spinal tap to do this test?
: Can this test tell me how long I have had an infection?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy