Pneumococcal Antibody Titration by Serological Cross-Immunoassay (Serum)
This test measures the amount of antibodies your body produces in response to pneumococcal bacteria, which can cause infections like pneumonia, bloodstream infections, or meningitis. It helps assess immunity after vaccination or exposure.
["Determines if your immune response to pneumococcal bacteria is adequate."]
Key facts at a glance
- LOINC
- 5254-8
- Short code
- M pneumo Ab Titr Ser CF
- Synonyms
- M pneumo Ab Titr Ser CF
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- comp-fix
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
Pneumococcal bacteria are common causes of serious infections, especially in people with weakened immune systems, young children, or the elderly. This test helps doctors check if your immune system has developed enough antibodies to protect you from these infections, particularly after receiving a pneumococcal vaccine.
When You Might Need This Test
Your doctor may recommend this test if you’ve had a pneumococcal vaccine but have symptoms of infection, if you’re at high risk for pneumococcal diseases (like those with chronic illnesses or immune deficiencies), or if you’re being evaluated for long-term immunity after vaccination.
How the Test Works
A small blood sample is taken from your arm and sent to a lab. The serum is tested using a method called immunoassay to measure the exact amount of antibodies specific to pneumococcal bacteria. This helps determine if your immune response is strong enough to protect you.
Sample Collection and Preparation
You’ll have a needle inserted into your vein to draw blood. The blood is then processed to separate the serum, which is sent to the lab for testing. No special preparation is needed, but avoid eating or drinking for a few hours before the test if instructed.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Pneumococcal Antibody Level
Frequently asked questions
Your doctor may use this test to confirm if you have adequate immunity against pneumococcal bacteria, especially after vaccination. Low antibody levels may indicate a need for booster shots or further evaluation of your immune system.
What does a low or high antibody level mean?
How long does it take to get results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy