Skip to content

Pneumococcal Nucleic Acid Detection in Urine (by Probe)

Published: August 9, 2026Updated: August 16, 2026

This test checks for genetic material from *Streptococcus pneumoniae* (pneumococcus) bacteria in your urine, helping identify infections caused by this common cause of pneumonia, meningitis, or bloodstream infections.

Quick summary

["A simple urine test to detect pneumococcal bacteria linked to serious infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
111564-1
Short code
M pneumo DNA BAS Ql NAA+n-prb
Synonyms
M pneumo DNA BAS Ql NAA+n-prb
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
non-probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms like fever, chest pain, confusion, or difficulty breathing—especially if you’ve been exposed to someone with pneumonia or have a weakened immune system. It’s also used in certain hospital settings to guide treatment for suspected bacterial infections.

How the Test Works

The test uses a probe to detect genetic material (nucleic acid) from *Streptococcus pneumoniae* in your urine. This method is highly sensitive and specific, meaning it can quickly identify the bacteria without growing them in a lab.

Sample Collection and Preparation

You’ll provide a clean urine sample (midstream or catheterized) in a sterile container. The sample is then processed in a specialized machine that analyzes the genetic material for pneumococcal presence.

What to Expect During the Test

The test is quick and painless. Results are typically available within hours or a few days, depending on lab processing. If positive, it confirms a pneumococcal infection, which can be treated with antibiotics.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine Pneumococcal NAAT

Frequently asked questions

A positive result indicates a current or recent infection by *Streptococcus pneumoniae*, which can cause severe illnesses like pneumonia, sepsis, or meningitis. Early detection helps guide appropriate antibiotic treatment and reduces complications.
What does a positive result mean?
A positive result means your urine contains genetic material from *Streptococcus pneumoniae*, strongly suggesting an active infection. This is a key finding for treating the infection promptly with antibiotics tailored to the bacteria.
Can this test be used for other infections?
No, this test specifically detects only *Streptococcus pneumoniae* (pneumococcal) bacteria. It does not identify other types of bacteria or viruses.
Results are usually available within 24 hours for most labs, though some may take up to 48 hours depending on the lab’s workflow. Follow-up with your healthcare provider for interpretation.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy