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Pneumococcal Nucleic Acid Detection in Nasopharyngeal Specimen (Qualitative Probe)

Published: August 9, 2026Updated: August 16, 2026

This test checks for genetic material from *Streptococcus pneumoniae* (pneumococcus) bacteria in your nose or throat using a molecular probe. It helps determine if you may have an infection caused by this bacteria.

Quick summary

["Quickly identifies possible pneumococcal infection with a simple nasal swab test."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
53255-6
Short code
M pneumo DNA # Spec NAA+probe
Synonyms
M pneumo DNA # Spec NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

How the Test Works

A swab is gently inserted into your nose to collect cells from your upper respiratory tract. The sample is then analyzed in a lab to detect genetic material from pneumococcal bacteria. This method is highly sensitive and can provide results in minutes.

What to Expect Before the Test

No special preparation is needed. You may have a slight discomfort or mild irritation when the swab is inserted, but it usually lasts only a few seconds. Avoid using nasal sprays or drops for 24 hours before the test if possible.

What the Test Results Mean

A positive result means the test detected genetic material from pneumococcus, suggesting you may have an infection. A negative result means no detectable genetic material was found, but this does not rule out infection entirely. Follow-up with your healthcare provider if symptoms persist.

When This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like fever, cough, difficulty breathing, or other signs of pneumonia, sinusitis, or ear infections, especially if they suspect pneumococcal bacteria as the cause.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Pneumococcal NA Test (Qualitative)

Frequently asked questions

Why is this test important?
This test helps quickly identify pneumococcal infections, which can be serious. Early detection allows for prompt treatment with antibiotics, reducing the risk of complications like pneumonia, meningitis, or bloodstream infections. It is particularly useful in high-risk groups, such as young children, elderly adults, and those with weakened immune systems.
What does a positive result mean?
A positive result indicates the presence of pneumococcal bacteria in your sample. Your healthcare provider will discuss next steps, which may include starting antibiotic treatment immediately to address the infection.
Can a negative result mean I don’t have an infection?
Not necessarily. While a negative result means no pneumococcal genetic material was detected in this sample, other bacteria or viruses could still be causing your symptoms. Your doctor may recommend additional tests or follow-up if symptoms continue.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy