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Neutrophil count in sputum (absolute)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of neutrophils, a type of white blood cell, found in your sputum (phlegm). Neutrophils help fight infections but can also indicate inflammation or other conditions.

Quick summary

["Assessing your immune response to respiratory infections or inflammation in your airways."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
108963-0
Short code
M pneumo IgA Msmt Ser
Synonyms
M pneumo IgA Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like persistent cough, thick phlegm, or signs of infection (such as fever). It helps determine if your body is responding to an infection or if inflammation is present in your lungs or airways.

What to Expect Before the Test

You’ll likely cough up sputum into a sterile container. If you’re unable to produce sputum, your provider may use a swab to collect it from your throat or nasal passages. Follow any specific instructions your provider gives you, such as avoiding certain medications or foods before the test.

How the Test Works

The collected sputum is analyzed under a microscope to count the number of neutrophils. This process helps identify if there’s an abnormal presence of these cells, which could signal infection, inflammation, or other respiratory conditions.

Possible Results and Their Meaning

High neutrophil counts in sputum may indicate an active infection (such as pneumonia, bronchitis, or cystic fibrosis), chronic inflammation, or exposure to irritants. Low counts might suggest a less active infection or other underlying conditions. Your results will be interpreted by your healthcare provider in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Sputum Neutrophil Count

Frequently asked questions

What does a high neutrophil count in sputum mean?
A high neutrophil count in sputum often points to an infection or severe inflammation in your respiratory tract. This could be due to bacterial infections, chronic lung diseases (like COPD or cystic fibrosis), or exposure to irritants. Your provider may recommend further testing or treatment to address the underlying cause.
What does a low neutrophil count in sputum mean?
A low neutrophil count in sputum may suggest a milder infection, viral respiratory illness, or that your body is not actively fighting a significant inflammatory response. However, it can also be normal if your infection is resolving. Always discuss your results with your healthcare provider for accurate interpretation.
Can this test be used to diagnose cystic fibrosis?
While this test can help assess inflammation or infection in the lungs, it is not a definitive diagnostic tool for cystic fibrosis. Your provider may use additional tests, such as genetic testing or sweat chloride tests, to diagnose cystic fibrosis.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy