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Serum Immunoglobulin G (IgG) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG), a type of antibody in your blood that helps fight infections and diseases.

Quick summary

["IgG helps protect your body from infections and supports long-term immunity."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
57009-3
Short code
M pneumo IgG sp2 Ser IA-aCnc
Synonyms
M pneumo IgG sp2 Ser IA-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does IgG Measure?

IgG is the most abundant antibody in your blood, playing a key role in defending against bacteria and viruses. It can also help your body recognize and remember past infections, which is why it’s important for long-term immunity. Levels can vary depending on your health, immune response, and exposure to infections.

Why Might You Need This Test?

Doctors may order an IgG test to check for immune system function, diagnose conditions like immunodeficiency, evaluate responses to vaccines, or monitor chronic diseases such as lupus or rheumatoid arthritis. It can also help assess how well your body is producing antibodies after an infection.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate the serum (the liquid part without clots) for testing. This test is typically done on serum, but plasma can also be used depending on the lab’s method.

Common Reasons for Testing

IgG testing is often used to diagnose or monitor conditions like HIV, tuberculosis, autoimmune diseases, or to check for proper immune response after vaccination. It can also help identify if someone has a weakened immune system due to genetic disorders, cancer treatments, or other health conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgG Level

Frequently asked questions

What Are Normal IgG Levels?
There isn’t a single set of reference ranges for IgG because levels can vary widely based on age, health status, and other factors. Low IgG levels may suggest an immune deficiency, while very high levels could indicate chronic infections, certain cancers, or autoimmune diseases. Your doctor will interpret the results in the context of your overall health.
How Often Should I Get This Test?
The frequency of IgG testing depends on your medical condition and why the test was ordered. Some people may need it once, while others with chronic conditions might have it checked regularly. Always follow your healthcare provider’s recommendations.
Can IgG Levels Change Over Time?
Yes, IgG levels can change due to infections, vaccinations, aging, or certain medical treatments. For example, IgG levels might drop after chemotherapy or if you have an autoimmune disease that affects antibody production. Your doctor will track changes over time to monitor your health.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy