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Pneumococcal IgG Antibody by Serotype (Mass Concentration) – Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the levels of antibodies in your blood that help your immune system fight pneumococcal bacteria, which can cause serious infections like pneumonia, meningitis, or bloodstream infections.

Quick summary

["Assesses your immune response to pneumococcal bacteria, useful for evaluating risk or monitoring treatment in certain conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
5256-3
Short code
M pneumo IgM Ser IA-aCnc
Synonyms
M pneumo IgM Ser IA-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects specific antibodies (IgG) produced in response to exposure to pneumococcal bacteria. These antibodies are part of your body’s defense system against infections caused by these bacteria. The result helps determine if your immune system has recognized and responded to the bacteria.

Why It Might Be Ordered

Your healthcare provider may order this test if you have a history of pneumococcal infections, are at high risk (e.g., due to weakened immune system, chronic illness, or age), or if you’re being considered for pneumococcal vaccination. It can also help monitor immune response after vaccination.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The blood is processed to separate serum (the liquid part without clotting factors), which is then tested for antibody levels. This process is quick and typically done in a lab.

What to Expect Before the Test

No special preparation is needed, but inform your provider if you’re on blood-thinning medications or have bleeding disorders. Avoid alcohol for 24 hours before the test if possible, as it may affect blood clotting.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High antibody levels may indicate past infection or vaccination success, while low levels could suggest poor immune response, increased infection risk, or underlying immune issues. This test is particularly valuable in guiding vaccination decisions or assessing immune function in high-risk patients.

Short name

IgG Antibody to Pneumococcal Bacteria

Frequently asked questions

What does a positive result mean?
A positive result means your immune system has produced antibodies against pneumococcal bacteria, which may indicate prior infection, vaccination, or natural immunity. However, antibody levels alone don’t guarantee protection against future infections.
Can this test be used to diagnose pneumonia?
No, this test alone cannot diagnose pneumonia. It measures antibodies, not active infection. If pneumonia is suspected, your provider may order additional tests, such as imaging or cultures.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times. Your healthcare provider will discuss the findings with you during your follow-up visit.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy