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Serum Protein Electrophoresis (24-Hour Urine Collection for Proteinuria)

Published: August 9, 2026Updated: August 17, 2026

This test measures the types and amounts of proteins found in your urine over 24 hours, often used to check for kidney issues or abnormal protein patterns.

Quick summary

["Assesses kidney function and detects unusual protein patterns in urine, which may signal kidney disease or other conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
72577-0
Short code
M Protein 24h MFr.DF Ur Elph
Synonyms
M Protein 24h MFr.DF Ur Elph
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
7.35
Ref high
7.45
Critical range
7.2 N/A – 7.6 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like frequent urination, swelling, or if tests suggest kidney problems. It helps identify whether certain proteins (like albumin) are leaking into your urine, which can indicate conditions like kidney disease or multiple myeloma.

How the Test Works

You’ll collect all urine for a full 24-hour period. The urine is then analyzed using electrophoresis to separate proteins by size and type. This helps determine if abnormal proteins are present.

Sample Collection Process

You’ll start by emptying your bladder at the beginning of the test period. Then, you’ll collect every drop of urine for the next 24 hours, storing it in a container. At the end, the urine is combined and sent to the lab for testing.

What to Expect After Testing

Results may take several days to process. Your doctor will review them to see if abnormal proteins are present, which could guide further testing or treatment plans.

Reference range

NCBI: pH 7.35-7.45N/A

Specimen: urine

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24-Hour Urine Protein Electrophoresis

Frequently asked questions

What Does This Test Measure?
This test measures the total protein content in urine and the distribution of different protein types. High levels of certain proteins (like albumin) can signal kidney damage or disease, while unusual patterns may suggest conditions like multiple myeloma or other metabolic disorders.
How Might Results Affect My Care?
If abnormal proteins are found, your doctor may recommend additional tests (like kidney function tests) or treatments to manage the underlying condition. Normal results usually mean your kidneys are filtering urine properly.
FAQ: What Should I Do If I Have Questions About My Results?
Ask your doctor or healthcare provider to explain the results in detail. They can help clarify what the findings mean for your health and next steps.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy