Urinalysis with Protein Electrophoresis (Quantitative Protein Fractionation)
This test measures different types of proteins in your urine using electrophoresis, a method that separates proteins based on size and charge. It helps identify abnormal protein patterns that may indicate kidney disease or other conditions.
["This test helps diagnose kidney problems or conditions affecting protein levels in urine."]
Key facts at a glance
- LOINC
- 51437-2
- Short code
- M Protein 2 Ur Elph-mCnc
- Synonyms
- M Protein 2 Ur Elph-mCnc
- Category
- chemistry
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- electrophoresis
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test if you have symptoms like frequent urination, swelling in your legs or ankles, foamy urine, or if you have a history of kidney disease. It can also be part of routine screening for certain conditions or after an injury.
What to Expect Before the Test
No special preparation is needed. You’ll provide a urine sample, typically collected in the morning. Avoid excessive protein-rich foods or drinks for 24 hours before testing if instructed by your provider.
How the Test Works
Your urine is analyzed using electrophoresis, which separates proteins into bands. Different bands represent various protein types, such as albumin, globulins, and other fragments. This helps identify abnormal patterns.
Possible Results and Interpretation
Abnormal results may show excess proteins (like albumin) in urine, which can signal kidney damage or disease. Your provider will discuss findings with you based on your symptoms and medical history.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: This test is critical for detecting kidney-related conditions, such as nephrotic syndrome, glomerulonephritis, or diabetic nephropathy. Elevated protein levels in urine can also indicate inflammation, infection, or metabolic disorders.
Short name
Protein Urine Profile
Frequently asked questions
What does a high or low protein result mean in this test?
Does this test require fasting?
How long does it take to get results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy