Serum Protein Electrophoresis (Qualitative)
This test measures the different types of proteins in your blood using a technique called electrophoresis. It helps identify abnormal protein patterns that may suggest conditions like multiple myeloma, liver disease, or other disorders.
["This test helps doctors spot unusual protein levels that could signal serious health issues."]
Key facts at a glance
- LOINC
- 50792-1
- Short code
- M Protein 3 MFr SerPl Elph
- Synonyms
- M Protein 3 MFr SerPl Elph
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 7.35
- Ref high
- 7.45
- Critical range
- 7.2 N/A – 7.6 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- electrophoresis
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
Electrophoresis separates blood proteins into fractions based on size and electrical charge. The test detects abnormal protein bands, such as monoclonal proteins (e.g., M proteins) that may appear in diseases like multiple myeloma or Waldenström macroglobulinemia. Normal results show distinct bands for albumin, globulins (including immunoglobulins), and other proteins.
Why Might Your Doctor Order This Test?
Your doctor may recommend this test if you have symptoms like unexplained fatigue, weight loss, frequent infections, or swollen glands. It’s also used to monitor conditions like chronic kidney disease, liver disease, or to check for hidden protein abnormalities in blood samples.
How Is This Test Performed?
A blood sample is drawn from a vein, usually in your arm. The serum (liquid part of blood without clots) is then analyzed in a lab using electrophoresis. The results are compared to standard patterns to identify any unusual protein distributions.
What Are Common Findings?
Normal results show balanced protein bands, including high albumin (a major protein) and various globulins (proteins like antibodies). Abnormal findings may include extra bands (e.g., M proteins) or missing bands, which could indicate immune system disorders, infections, or metabolic issues.
Reference range
NCBI: pH 7.35-7.45N/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Protein Electrophoresis (Serum)
Frequently asked questions
What Does It Mean If My Results Are Abnormal?
How Often Should I Get This Test?
What Should I Do If I Have Symptoms Like Fatigue or Swollen Glands?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy