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Total Protein in Urine (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein found in your urine, which can help identify whether your kidneys are functioning properly or if there is an abnormal protein loss.

Quick summary

["Assesses kidney health and potential protein loss in urine."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
87833-0
Short code
M Protein 3 Ur IFE-mCnc
Synonyms
M Protein 3 Ur IFE-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
immunofixation
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for conditions like kidney disease, proteinuria (excess protein in urine), or other metabolic disorders. It can also be used to monitor treatment progress or detect early signs of kidney problems.

What Does a High or Low Result Mean?

Elevated protein levels in urine may suggest kidney damage, inflammation, or other systemic issues. Very low levels might indicate dehydration or certain medical conditions. Results alone don’t diagnose a condition without clinical correlation.

How Is the Test Performed?

A small urine sample is collected, typically over a 24-hour period or a single random sample, depending on the test protocol. The sample is then analyzed in a lab using specialized techniques to measure protein concentration.

What Are Common Causes of Abnormal Results?

High urine protein levels can result from kidney diseases (e.g., glomerulonephritis), diabetes, pregnancy, or certain infections. Low levels may occur due to dehydration, liver disease, or malnutrition.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is critical for diagnosing and monitoring kidney function, detecting protein loss associated with systemic diseases, and guiding treatment decisions. It helps identify conditions like nephrotic syndrome, diabetic nephropathy, or early-stage kidney failure.

Short name

Urine Protein Test

Frequently asked questions

What should I expect before the test?
No special preparation is usually needed, but you may be asked to avoid certain medications or foods that could interfere with results. Follow your provider’s instructions carefully.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times. Your healthcare provider will discuss them with you during your follow-up visit.
Can I drink water before the test?
Yes, drinking water is generally fine unless instructed otherwise by your provider, as it helps ensure an accurate urine sample volume for 24-hour collection.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy