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Urinalysis with Protein Electrophoresis (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the breakdown of urine proteins using electrophoresis, a method that separates different protein types by size and charge. It helps identify patterns of protein loss or abnormal protein profiles.

Quick summary

["This test helps diagnose conditions affecting kidney function or protein metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
59563-7
Short code
M Protein 4 Ur Elph-mCnc
Synonyms
M Protein 4 Ur Elph-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like foamy urine, swelling, or unexplained protein in blood tests. It’s also used to check for conditions like multiple myeloma, kidney disease, or certain metabolic disorders.

How the Test Works

A small urine sample is collected and analyzed using electrophoresis. Proteins in the urine are separated into bands, which are then examined for abnormal patterns or high concentrations of specific proteins.

Sample Collection

Urine is typically collected in a clean container, often first-morning urine for best accuracy. Follow your provider’s instructions to avoid contamination or dilution.

What to Expect

No special preparation is usually needed, but you may be asked to avoid certain medications or foods that could interfere with results. Results may take a few days to process.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal protein patterns can indicate kidney disease (e.g., nephrotic syndrome), multiple myeloma, or other conditions causing abnormal protein production. High levels of certain proteins may also signal metabolic or inflammatory disorders.

Short name

Protein Urine Electrophoresis

Frequently asked questions

What causes abnormal protein results in urine?
Abnormal protein results can occur due to kidney damage, infections, certain cancers (like multiple myeloma), or metabolic disorders. Symptoms like swelling, fatigue, or unexplained weight changes may also prompt testing.
How long does it take to get results?
Results are typically available within 2–5 business days, depending on lab processing times. Follow-up with your provider if you have questions about your results.
Can diet affect this test?
Yes, certain foods (e.g., high-protein diets) or medications (e.g., NSAIDs) may influence protein levels. Avoid these for 24 hours before testing if instructed by your provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy