Skip to content

Serum Protein Electrophoresis by Bromocresol Purple (BCP) Method

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of different protein fractions in your blood serum using an electrophoresis technique with bromocresol purple dye. It helps identify abnormalities in protein composition, which can indicate conditions like multiple myeloma, liver disease, or other metabolic disorders.

Quick summary

["This test helps doctors understand how proteins are balanced in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
56767-7
Short code
M protein beta Ur Elph-mCnc
Synonyms
M protein beta Ur Elph-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if they suspect conditions affecting protein levels, such as kidney disease, liver problems, or certain cancers. It can also be part of routine monitoring for chronic conditions like diabetes or autoimmune diseases. Symptoms like swelling, unexplained weight loss, or fatigue may prompt this test.

How the Test Works

A small blood sample is drawn and separated into different protein fractions based on their size and electrical charge. The bromocresol purple dye binds to specific proteins, allowing for visual separation on a gel. The results show bands representing various protein groups, including albumin, globulins, and others.

Sample Collection and Preparation

Blood is collected from a vein in your arm by a healthcare professional. The sample is then processed and sent to a lab for analysis. No special preparation is needed, but fasting may be advised depending on your provider’s instructions.

Interpreting Results

Results are typically presented as a graph or pattern showing the relative amounts of different protein types. Abnormal patterns may indicate high or low levels of specific proteins, which can guide further testing or treatment planning.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal protein electrophoresis can signal underlying health issues. For example, a spike in certain globulins might suggest multiple myeloma or other plasma cell disorders, while altered albumin levels could point to liver or kidney disease. Your provider will discuss the results in the context of your symptoms and medical history.

Short name

Serum Protein Electrophoresis

Frequently asked questions

What Does an Abnormal Result Mean?
An abnormal result doesn’t necessarily mean you have a serious condition. It may just indicate a need for further evaluation. Your healthcare provider will explain what the results mean for your specific situation and recommend next steps, if any.
How Often Should I Get This Test?
The frequency depends on your health condition and symptoms. Some people need this test once a year or more often if they have chronic illnesses like kidney disease or cancer. Always follow your provider’s advice on how often to get tested.
Can I Prepare for This Test?
Generally, no special preparation is needed. However, check with your provider if they recommend fasting or avoiding certain medications before the test.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy