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Total Protein in Urine (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein present in your urine, which can help identify whether protein is leaking from your bloodstream into your kidneys or other parts of your body.

Quick summary

["Assessing kidney function and detecting abnormal protein loss through urine."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35560-2
Short code
M Protein Ur-mCnc
Synonyms
M Protein Ur-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Matters

Protein in urine can signal underlying health issues, such as kidney disease, diabetes, or other conditions that affect how your body filters waste. High levels may indicate damage to your kidneys or other organs.

What to Expect Before the Test

No special preparation is needed, but you may be asked to collect a urine sample in a clean container. If you’re using certain medications or have health conditions, let your provider know before testing.

Common Causes of Protein in Urine

Proteinuria can result from kidney problems (like glomerulonephritis), high blood pressure, diabetes, infections, or certain medications. Stress, fever, or intense exercise can also temporarily raise protein levels.

What the Results Mean

Results are typically reported in grams per liter (g/L) or milligrams per deciliter (mg/dL). Abnormal results may prompt further testing to find the cause, such as kidney function tests or imaging.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated urine protein levels often signal kidney damage or dysfunction, which can worsen if untreated. Early detection helps manage conditions like chronic kidney disease, diabetes nephropathy, or other systemic issues. Low levels may be normal, but persistent changes warrant medical evaluation.

Short name

Urine Protein Mass

Frequently asked questions

Will I feel different after this test?
No, you won’t feel any side effects from the urine test itself. If you’re concerned about discomfort, ensure you’re using a clean container and follow proper collection instructions.
How often should I get this test?
Your doctor will determine the frequency based on your health history, symptoms, and other tests. Regular monitoring may be needed if you have kidney disease, diabetes, or other risk factors.
Can diet or medications affect this test?
Yes, certain foods (like high-sodium or protein-rich meals) and medications (e.g., NSAIDs, some antibiotics) can temporarily influence protein levels. Avoid these 24 hours before testing if instructed.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy