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Serum or plasma anti-endomysial antibody (qualitative) by immunofluorescence

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies against endomysium, a protein found in the lining of muscle fibers in the small intestine. It is commonly used to help diagnose celiac disease.

Quick summary

["This test helps detect celiac disease by checking for specific antibodies linked to gluten sensitivity."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30865-0
Short code
MRA Celiac ves+SM ves
Synonyms
MRA Celiac ves+SM ves
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
mr-angio
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is This Test Measuring?

The test looks for anti-endomysial antibodies in your blood. These antibodies are produced when your immune system mistakenly attacks the lining of your small intestine due to gluten exposure. The presence of these antibodies can indicate an ongoing immune response associated with celiac disease.

Why Might Your Doctor Order This Test?

Your doctor may recommend this test if you have symptoms like persistent diarrhea, weight loss, fatigue, or abdominal pain, or if you have a family history of celiac disease. It can also be used as part of a screening process for unexplained gastrointestinal issues.

What Does a Positive Result Mean?

A positive result suggests a high likelihood of celiac disease, prompting further testing such as an intestinal biopsy. However, a negative result does not definitively rule out celiac disease, so other diagnostic steps may still be needed.

What Should You Expect During the Test?

The test involves drawing blood from a vein in your arm. The sample is then analyzed in a lab to detect the presence of anti-endomysial antibodies. The process typically takes about 15 minutes and is usually painless.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Anti-endomysial antibodies are highly specific markers for celiac disease. When detected, they signal an immune-mediated damage to the small intestine, which can lead to malabsorption of nutrients. Early diagnosis through antibody testing, combined with a gluten-free diet and biopsy confirmation, is crucial for managing symptoms and preventing long-term complications.

Short name

Anti-Endomysial Antibody (qIF)

Frequently asked questions

How soon can I expect results?
Results from this test are usually available within 1 to 3 business days, depending on your lab’s processing schedule. Your healthcare provider will contact you once they have the results.
What if my test results are positive?
If your anti-endomysial antibody test is positive, your doctor will likely recommend additional testing, such as an intestinal biopsy. This involves taking a small tissue sample from your small intestine to confirm damage caused by celiac disease. Follow-up care will focus on managing symptoms and ensuring proper nutrition.
Can I eat gluten before this test?
Yes, you can eat your regular diet before this test. Unlike some other celiac disease tests, anti-endomysial antibodies are not affected by gluten intake, so there is no need to avoid it beforehand.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy