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Serum Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood serum. It helps assess kidney function.

Quick summary

["A creatinine test helps doctors check how well your kidneys are filtering waste from your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
102454-6
Short code
M racemosus IgE RAST
Synonyms
M racemosus IgE RAST
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
rast
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine is a byproduct of muscle breakdown and is filtered out by your kidneys. High levels can indicate reduced kidney function or damage, while low levels may suggest overhydration or other conditions. This test is often used alongside other measures like blood urea nitrogen (BUN) to evaluate kidney health.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a broader metabolic panel. Drink plenty of water the day before to ensure accurate results. Avoid heavy exercise or extreme dehydration, as these can affect creatinine levels.

What the Results Mean

Results are typically reported in milligrams per deciliter (mg/dL) or millimoles per liter (mmol/L). While reference ranges vary by lab, consistently high or low values may signal kidney issues, dehydration, or other health concerns that require further evaluation.

Common Causes of Abnormal Results

Elevated creatinine levels may occur due to kidney disease, dehydration, severe muscle damage, or conditions like heart failure. Low levels can result from overhydration, liver disease, or certain medications. Always discuss results with your healthcare provider.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is critical for monitoring kidney function, diagnosing conditions like chronic kidney disease, and guiding treatment plans for patients with diabetes, hypertension, or other chronic illnesses. It’s also used in pre-surgery evaluations to assess overall health.

Short name

Creatinine

Frequently asked questions

What triggers a creatinine test?
A creatinine test may be ordered if you have symptoms like fatigue, swelling, or frequent urination; if you have a history of kidney disease, diabetes, or high blood pressure; or if you’re preparing for surgery. Your doctor may also recommend it as part of routine check-ups for certain risk factors.
How long does it take to get results?
Results are typically available within 24–48 hours, depending on your lab’s processing time. Some labs offer same-day or next-day results for urgent cases, but follow-up with your healthcare provider is always recommended to interpret the findings.
Can diet or exercise affect creatinine levels?
Yes, diet (especially protein intake) and exercise can influence creatinine levels. High-protein diets may temporarily raise creatinine, while dehydration can elevate it. Staying hydrated and discussing your diet with your doctor can help ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy