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Serum or plasma concentration of extracellular matrix protein (e.g., related to fibrosis markers)

Published: August 9, 2026Updated: August 16, 2026

This test measures levels of proteins found outside your cells, which can help assess conditions like fibrosis (scarring) in organs.

Quick summary

["This test helps evaluate organ damage or scarring from chronic conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30876-7
Short code
MRA Extr vv
Synonyms
MRA Extr vv
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
mr-angio
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Extracellular matrix proteins are components that support and structure tissues. Elevated levels may indicate abnormal tissue growth or scarring, often seen in diseases like cirrhosis, interstitial lung disease, or other fibrotic conditions. This test may be used to monitor progression or response to treatment in these cases.

Why It’s Ordered

Your healthcare provider may order this test if you have symptoms of organ damage (e.g., fatigue, abdominal pain, shortness of breath) or if you have a known condition linked to fibrosis, such as liver disease, lung disease, or connective tissue disorders.

What to Expect Before the Test

No special preparation is typically needed. You may provide a blood sample (serum or plasma) or, in some cases, urine or other fluids. Follow your provider’s instructions if you’re on certain medications or have dietary restrictions.

What to Expect During the Test

A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch, but it usually takes only a few minutes. If urine or saliva is involved, you’ll follow standard collection instructions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated levels of extracellular matrix proteins can signal ongoing tissue damage or fibrosis. For example, high levels might indicate worsening liver disease, lung scarring, or other chronic inflammatory conditions. Low levels could suggest reduced production of these proteins, though this is less common. Results help guide treatment decisions or monitor disease activity.

Short name

Extracellular Matrix Protein Level

Frequently asked questions

How long will results take?
Results are usually available within 1–3 business days, depending on lab processing times. Your provider will discuss findings with you during your follow-up visit.
Can I eat or drink before this test?
No special diet is required for blood tests, but avoid alcohol for 24 hours before your appointment if your provider instructed you to. For urine-based tests, follow any specific instructions (e.g., fasting or avoiding certain foods).
Will this test affect my medications?
This test itself does not interact with medications, but some conditions or treatments (e.g., liver disease management) may influence results. Always inform your provider about all medications, supplements, or recent treatments.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy