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Magnetic Resonance Imaging (MRI) of the Head With and Without Intravenous Contrast

Published: August 9, 2026Updated: August 16, 2026

This imaging test creates detailed pictures of the brain and nearby structures, first without contrast and then after an IV contrast agent is given.

Quick summary

["A head MRI with and without contrast helps doctors examine the brain for structural or vascular abnormalities."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
36847-2
Short code
MRA Head vv WO+W contr IV
Synonyms
MRA Head vv WO+W contr IV
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
mr-angio
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test is a magnetic resonance imaging (MRI) examination of the head. It produces detailed pictures of the brain and surrounding tissues and may include images taken before and after an intravenous contrast agent is administered.

Why might I need this test?

A head MRI may be ordered to investigate symptoms such as severe headache, weakness, seizures, vision changes, confusion, or head injury. It can help evaluate the brain for conditions including stroke, tumors, infection, inflammation, fluid buildup, and other structural abnormalities.

How is the test performed?

You will lie on a movable table inside an MRI scanner, which uses a strong magnetic field and radio waves to create images. If contrast is included, it is usually given through a small intravenous line in your arm; the scan may take longer and you may be asked to remain still.

How do I prepare for the test?

Follow the imaging center's instructions, as fasting may or may not be required. Tell the care team if you have metal implants, a pacemaker, kidney disease, a prior contrast reaction, or possibly being pregnant, because these factors can affect safety or the choice of contrast.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal MRI findings may indicate a condition affecting the brain, such as a tumor, stroke, bleeding, infection, inflammation, or abnormal fluid accumulation. The radiologist will interpret the images in the context of your symptoms and examination, and additional testing may be needed to determine a diagnosis.

Short name

Head MRI with and without IV contrast

Frequently asked questions

What is the difference between MRI with and without contrast?
Images without contrast show basic anatomy and may be sufficient for many concerns. Contrast can make certain tissues, blood vessels, inflammation, and abnormal areas easier to see.
Is IV contrast safe?
Most people tolerate the contrast used for head MRI well, but kidney problems or a previous serious reaction can increase risk. Your care team should review any relevant allergies, medical conditions, and kidney function before giving contrast.
Will I need to stay overnight or undergo another procedure?
No. This is usually an outpatient imaging test performed in about 30 to 60 minutes, although timing varies with the scanner and the complexity of the examination. Any additional imaging or testing will depend on the results and your doctor's assessment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy