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Serum or plasma mass concentration of malondialdehyde (MDA)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of malondialdehyde, a breakdown product of fats that can indicate oxidative stress in your body.

Quick summary

["Malondialdehyde helps assess how your cells are being damaged by free radicals over time."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
36784-7
Short code
MRA LE vv-L
Synonyms
MRA LE vv-L
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
mr-angio
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Malondialdehyde?

Malondialdehyde (MDA) is a chemical compound formed when fats in your body break down due to oxidative stress. While small amounts occur naturally, higher levels may suggest increased cell damage from factors like inflammation, certain medications, or underlying health conditions.

Why Might You Need This Test?

Your healthcare provider may order this test to evaluate oxidative damage, monitor conditions like chronic kidney disease, or assess the effects of treatments that increase free radical production.

Common Uses and Conditions

This test is less commonly used than others but may be part of broader assessments for oxidative stress in specific clinical scenarios, such as evaluating damage from certain medications or metabolic disorders.

What to Expect Before the Test

No special preparation is typically required, but you may need to fast or avoid certain foods/drinks depending on your lab protocol. Bring any medications you’re taking to discuss with your provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated MDA levels may signal oxidative stress, which can contribute to chronic inflammation, organ damage, or complications in conditions like diabetes, kidney disease, or cardiovascular disorders. However, MDA is not a standalone diagnostic test and is often interpreted alongside other markers.

Short name

MDA Level

Frequently asked questions

How is this test different from other oxidative stress tests?
Unlike tests like glutathione or vitamin E, MDA specifically measures a direct product of lipid peroxidation, making it unique in assessing fat breakdown damage. It’s less frequently used than broader oxidative stress panels but can be valuable in specific research or specialized clinical settings.
What does a high or low MDA level mean?
A high MDA level suggests increased oxidative stress, which may indicate underlying health concerns. A low level doesn’t necessarily mean your body is healthy, as MDA is just one marker among many. Your provider will interpret results in the context of your overall health and symptoms.
Can diet or lifestyle changes affect MDA levels?
Yes, diet, exercise, and certain supplements (like antioxidants) can influence oxidative stress. Reducing processed foods, increasing fruits/vegetables, and managing stress may help lower MDA levels over time, but results may take weeks to reflect changes.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy