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Vitamin E (alpha-tocopherol) in lower leg venous serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vitamin E, a fat-soluble antioxidant, in your blood drawn from your lower leg. Vitamin E helps protect cells from damage caused by free radicals.

Quick summary

["Vitamin E supports cell health and may help reduce oxidative stress in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
43513-1
Short code
MRA Lower leg ves-L
Synonyms
MRA Lower leg ves-L
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
mr-angio
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might This Test Be Ordered?

Your healthcare provider may order this test to assess your vitamin E levels if you have symptoms like muscle weakness, nerve problems, or if you have conditions that affect fat absorption (e.g., certain gastrointestinal disorders). It can also be part of a broader evaluation for deficiencies or monitoring treatment for conditions linked to oxidative stress.

What Does a Low or High Level Mean?

Low levels might indicate a vitamin E deficiency, which can affect nerve function and muscle health. High levels could suggest vitamin supplementation or rare genetic conditions. Your results will be compared to general reference ranges for healthy adults.

How Is This Test Performed?

A blood sample is taken from your lower leg vein. The blood is then processed to separate serum, which is analyzed for vitamin E content using a specialized laboratory method.

What Are Common Causes of Abnormal Results?

Deficiencies may arise from poor diet, malabsorption issues, or certain medications. Overconsumption of vitamin E supplements can lead to elevated levels. Chronic liver disease or genetic disorders may also influence results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Vitamin E plays a critical role in protecting cell membranes from oxidative damage. Low levels can impair nerve function and increase susceptibility to oxidative stress-related diseases. This test helps identify potential deficiencies or excesses that may require medical attention.

Short name

Vitamin E (alpha-tocopherol) level

Frequently asked questions

What does a vitamin E test measure?
This test measures the concentration of alpha-tocopherol, the biologically active form of vitamin E, in your blood serum. It helps evaluate your antioxidant status and overall vitamin E levels.
How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing schedule. Your healthcare provider will discuss the findings with you during your follow-up visit.
Can I take vitamin E supplements before the test?
It’s best to avoid taking high-dose vitamin E supplements for at least 2 weeks before testing unless instructed by your provider. This helps ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy