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Serum or Plasma Creatinine Concentration (Standard Method)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess how well your kidneys are filtering blood.

Quick summary

["Kidney function check via creatinine levels in blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
37497-5
Short code
MRA Spine ves
Synonyms
MRA Spine ves
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
mr-angio
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine levels can indicate how well your kidneys are working. High levels may suggest kidney problems, while low levels could signal dehydration or other conditions. This test is often used alongside other kidney function tests to diagnose or monitor kidney disease.

What to Expect Before the Test

You may be asked to fast before the test, but this isn’t always required. Avoid strenuous activity or consuming large amounts of protein-rich foods 24 hours before testing. Drink plenty of water the day before if you’re not restricted.

Sample Collection Process

A blood sample is drawn from a vein, usually in your arm. You may feel a slight pinch, but it’s a quick and painless procedure. The sample is sent to a lab for analysis.

What the Results Mean

Results are compared to a reference range specific to your age, sex, and overall health. Abnormally high levels may signal kidney issues, while very low levels might indicate dehydration or other medical conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Creatinine

Frequently asked questions

How often should I get this test?
Your doctor will determine the frequency based on your health status. For example, people with kidney disease may need regular monitoring, while others might only need it occasionally.
Can diet affect my creatinine levels?
Yes, high-protein diets can temporarily increase creatinine levels. Avoid excessive protein intake before testing, but don’t restrict it unnecessarily unless advised by your doctor.
What if my results are abnormal?
If your results are outside the expected range, your doctor will discuss them with you. They may recommend further tests, adjustments to your treatment, or additional follow-ups to understand and manage the issue.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy