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Serum or Plasma Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle breakdown, in your blood. It helps assess how well your kidneys are filtering blood.

Quick summary

["Kidney function and waste removal depend on this test."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
36080-0
Short code
MRA UE vv
Synonyms
MRA UE vv
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
mr-angio
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for kidney problems, monitor kidney disease, or evaluate how well medications are being processed by your kidneys. It can also help diagnose conditions like dehydration, heart failure, or muscle disorders.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a metabolic panel. Drink plenty of water the day before to ensure normal kidney function. Avoid heavy exercise or strenuous activity.

What Happens During the Test?

A healthcare provider will draw blood from a vein in your arm. You may feel a slight pinch, but it’s quick and usually not painful. The blood sample is sent to a lab for analysis.

What Are Normal Results?

Results vary by age, sex, and overall health. Your doctor will compare your results to your baseline or to standard ranges appropriate for your situation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High creatinine levels may indicate kidney damage, poor kidney function, or conditions like dehydration or heart problems. Low levels could suggest overhydration or liver disease, though this is less common. Always discuss results with your doctor.

Short name

Creatinine Level

Frequently asked questions

What causes creatinine levels to change?
Creatinine levels can rise due to kidney disease, dehydration, severe muscle injury, or certain medications. They may drop if you’re overhydrated or have liver disease. Age, sex, and muscle mass also affect results.
How often should I get this test?
Your doctor will determine how often you need this test based on your health history, symptoms, and treatment plan. Regular monitoring may be needed if you have chronic kidney disease or other conditions affecting kidney function.
Can diet affect creatinine levels?
Dietary protein intake can influence creatinine levels, but the effect is usually small. Avoiding excessive protein or salt may help if your doctor recommends it for kidney health, but always follow their guidance.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy