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C-reactive protein (high-sensitivity) in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein produced by your liver in response to inflammation, helping doctors assess low-level inflammation in your body.

Quick summary

["hs-CRP helps track subtle inflammation that may not show up in other tests."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
36081-8
Short code
MRA Vena cava
Synonyms
MRA Vena cava
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
mr-angio
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order hs-CRP to monitor chronic conditions like heart disease, arthritis, or other inflammatory disorders. It’s also used to check for early signs of infection or inflammation after surgery or injury.

How Is the Sample Collected?

A small needle will draw blood from a vein in your arm. You may feel a brief pinch, but it usually stops quickly. The blood is sent to a lab for testing.

What Does a High or Low Result Mean?

Higher-than-normal levels may indicate inflammation, infection, or conditions like autoimmune diseases. Lower-than-normal levels might suggest reduced inflammation, but they don’t always mean you’re healthy.

Common Conditions Monitored With This Test

hs-CRP is often used alongside other tests to guide treatment for heart disease, rheumatoid arthritis, or after procedures like bypass surgery to prevent complications.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

hs-CRP

Frequently asked questions

What does a high hs-CRP level mean?
A high hs-CRP level suggests inflammation is active in your body, which could be linked to infections, autoimmune conditions, or chronic diseases like heart disease. Your doctor will discuss this with you in detail.
How often should I get this test?
The frequency depends on your health condition. If you have a chronic illness, your doctor may recommend regular check-ups. If you’re healthy, this test is usually not routine unless you have risk factors.
Can lifestyle changes affect hs-CRP levels?
Yes! Diet, exercise, and managing stress can lower inflammation. Quitting smoking, eating heart-healthy foods, and staying active may help reduce hs-CRP levels over time.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy