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Bromocresol Purple Protein Electrophoresis (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures protein fractions in your blood using a dye called bromocresol purple to separate and analyze different protein types.

Quick summary

["It helps identify abnormal protein patterns that may signal conditions like multiple myeloma or other blood disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
37220-1
Short code
MR BD+PD
Synonyms
MR BD+PD
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
mr
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test uses electrophoresis to split serum proteins into bands based on size and charge. Bromocresol purple binds to proteins, shifting their migration and creating distinct zones that reflect protein composition.

Why It’s Done

Doctors order this test to diagnose or monitor conditions affecting protein balance, such as plasma cell dyscrasias (e.g., multiple myeloma) or hereditary disorders like alpha-1 antitrypsin deficiency.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in the arm. The serum (liquid part after clotting) is separated and prepared for electrophoresis on a specialized gel.

What to Expect Before the Test

No special preparation is needed, but inform your provider if you’re on blood-thinning medications or have a history of bleeding disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test plays a critical role in detecting abnormal protein patterns that may indicate systemic diseases. For example, an increased monoclonal spike could signal multiple myeloma, while specific band shifts may reveal hereditary protein deficiencies.

Short name

BCP Protein Electrophoresis

Frequently asked questions

What causes abnormal protein electrophoresis results?
Abnormal results often stem from conditions like multiple myeloma (excess monoclonal proteins), hereditary disorders (e.g., alpha-1 antitrypsin deficiency), or chronic inflammatory diseases. Your doctor will correlate findings with symptoms and other tests.
How long does it take to get results?
Results are typically available within 24–48 hours, depending on lab processing times. Follow-up may require additional testing or a doctor’s consultation.
Can I eat or drink before this test?
No special diet is required, but avoid alcohol 24 hours before testing, as it may affect protein levels.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy