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Mass concentration of total bilirubin in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin, a yellow pigment produced when red blood cells break down. It helps assess liver function and bile flow.

Quick summary

["A bilirubin test checks for liver or bile duct issues and red blood cell breakdown."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
38058-4
Short code
MR Brst-R for Implant
Synonyms
MR Brst-R for Implant
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
mr
CPT
86430
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to diagnose or monitor conditions like jaundice (yellowing of skin/eyes), liver disease (such as hepatitis or cirrhosis), bile duct blockages, or hemolytic anemia (rapid red blood cell destruction). It can also help evaluate liver function before surgery or during treatment for certain conditions.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it’s part of a liver function panel. Bring any medications or supplements you’re taking, as they could affect results.

How the Test Is Performed

A healthcare provider will draw blood from a vein in your arm using a small needle. You may feel a brief pinch, but it usually doesn’t cause discomfort. The blood sample is sent to a lab for analysis.

What the Results Mean

Results are typically reported in milligrams per deciliter (mg/dL). High levels may indicate liver problems, bile duct blockages, or red blood cell disorders. Low levels are less common but may suggest liver disease or certain genetic conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total bilirubin

Frequently asked questions

What causes elevated bilirubin?
Elevated bilirubin can result from liver problems (like hepatitis or cirrhosis), blockages in the bile ducts, or conditions that cause red blood cells to break down faster than the liver can process the bilirubin. Lifestyle factors, medications, or genetic disorders may also play a role.
What should I do if my bilirubin is high?
If your bilirubin is elevated, your doctor may recommend additional tests to pinpoint the cause, such as imaging studies (like an MRI or ultrasound) or further liver function tests. Follow their advice for monitoring or treatment, which could include dietary changes, medications, or lifestyle adjustments.
Can diet affect bilirubin levels?
Diet alone rarely affects bilirubin levels, but certain foods (like high-fiber or fatty foods) may influence liver function indirectly. Avoiding alcohol or certain medications can also help prevent liver strain that might raise bilirubin. Always discuss dietary changes with your healthcare provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy