Localization of a Suspected Lesion by Serum/Plasma Protein Electrophoresis (Screening)
This test measures the different types of proteins in your blood to help identify abnormalities that might indicate conditions like infections, inflammation, or certain cancers. It’s often used as an initial screening step.
["A simple blood test to check for unusual protein patterns that could signal health concerns."]
Key facts at a glance
- LOINC
- 107420-2
- Short code
- MR Guide Brst-R seeds localize lesion
- Synonyms
- MR Guide Brst-R seeds localize lesion
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- mr
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
Serum protein electrophoresis separates proteins into fractions (such as albumin, alpha-globulins, beta-globulins, and gamma-globulins) using an electric field. This helps detect abnormal protein levels that may appear in conditions like multiple myeloma, lymphoma, or other disorders affecting protein production.
Common Uses and Indications
Doctors may order this test when symptoms suggest possible protein abnormalities, such as unexplained weight loss, fatigue, swollen lymph nodes, or unexplained fever. It’s also used in monitoring certain chronic diseases.
How the Test Works
A small blood sample is drawn and sent to a lab. The serum is then separated and run through an electrophoresis gel, where proteins migrate based on size and charge. Results are interpreted to identify any unusual bands or shifts in protein distribution.
Preparation and Procedure
No special preparation is needed, but fasting may not be required. A healthcare provider will insert a needle into your arm to collect blood. The process is quick and usually painless.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Serum Protein Electrophoresis (Screening)
Frequently asked questions
This test can help diagnose conditions like multiple myeloma (cancer of plasma cells), monoclonal gammopathy of undetermined significance (MGUS), or other protein-related disorders. Abnormal patterns may also signal infections, liver disease, or autoimmune conditions.
What does it mean if my results show abnormal protein bands? Abnormal bands may indicate an underlying condition that requires further testing, such as a biopsy or additional bloodwork, to determine the cause.
Is there any risk or discomfort associated with this test? The procedure involves a small needle prick, which may cause mild discomfort, but most people tolerate it well. Rarely, there may be bruising or slight bleeding at the site.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy